Lymphocyte subpopulations of lymph nodes and spleens in Hodgkin's disease
نویسندگان
چکیده
منابع مشابه
CD8+ T Lymphocyte Subsets in Bladder Tumor Draining Lymph Nodes
Background: Cytotoxic CD8+ T cells, as essential parts of the adaptive immune system, play pivotal roles in anti-tumor immune responses. It is well documented that cytokine expression profiles and activation status of these cells during anti-tumor immune responses affect the outcome of host-tumor interaction. Objective: To investigate the percentages of CD8+ lymphocytes and their subsets in...
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متن کاملIn situ immunologic characterization of cellular constituents in lymph nodes and spleens involved by Hodgkin's disease.
The cellular constituents in lymph nodes and spleens of patients with Hodgkin's disease were studied with a series of monoclonal antibodies directed against human thymocyte, peripheral T-cell, and la antigens. Utilizing both an immunoperoxidase technique on frozen tissue sections and indirect immunofluorescence on cell suspensions, wer found that a majority of lymphocytes were T cells, since th...
متن کاملNatural killer activity in spleens and lymph nodes from patients with Hodgkin's disease.
Natural killer (NK) activity against K-562 myeloid cell line was evaluated in 21 spleens and 14 lymph nodes from patients with Hodgkin's disease (HD). NK activity of eight HD-involved (HD+) spleens [556 lytic units (LU)] was found 5-fold higher than that of 13 HD-uninvolved (HD-) spleens (112 LU) (p less than 0.01). Moreover, NK activity of HD+ spleens was significantly different (p less than 0...
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ژورنال
عنوان ژورنال: Cancer
سال: 1978
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(197809)42:3<1270::aid-cncr2820420336>3.0.co;2-t